Assessment of Hematological and Hormonal levels of PCOS subjects: a case-control study

Polycystic ovarian syndrome (PCOS) is one of the most common endocrine disorders in reproductive-aged women. PCOS is considered to be a complex disease that affects childbearing age, adolescents and postmenopausal women. A significant number of cases were found in and around Tamil Nadu. The study recruited 65 (PCOS subjects) experimental and 65 age-matched controls (±5 years). Again, they were classified into three groups (Group I, II and III) based on age duration. The hematological and hormonal activities were analysed using laboratory technique. Epidemiological data were documented in clinical records including acne, hirsutism, irregular periods and obesity (BMI). Obesity, irregular periods, hirsutism and oily skin type were observed. Among the findings, higher BMI level 30%, irregular periods 46%, hirsutism 10% and oily skin type 40% were found in PCOS. The mean level of hematological parameters appears to be insignificant compared to PCOS and controls. FSH and LH hormone levels were estimated. FSH and LH levels were significantly elevated in PCOS subjects. The findings of the study indicate that no associations were found in the hematological parameters but a larger sample size is required for future studies.