PD‐L1 Expression is Mediated by microRNA Processing, Wnt/β‐Catenin Signaling, and Chemotherapy in Wilms Tumor
Together, our results identify clinical and biological properties regulating PD-L1 in Wilms tumor that may inform precision therapy approaches in pediatric immuno-oncology.
Authors
- Matthew E. Campbell (ORCID: https://orcid.org/0000-0003-3325-240X)
- Sean D. Reiff (ORCID: https://orcid.org/0009-0004-3871-6861)
- Kenneth Chen (ORCID: https://orcid.org/0000-0003-2304-4631)
- Kavita Desai (ORCID: https://orcid.org/0000-0003-2406-8432)
- Arash Nabbi (ORCID: https://orcid.org/0000-0002-3195-7361)
- Patricia D.B. Tiburcio (ORCID: https://orcid.org/0000-0001-7978-1767)
- James F. Amatruda (ORCID: https://orcid.org/0000-0002-9901-2137)
- Shuxing Zhou
- Austin Warne
Institutions
- University of Southern California (US)
- Children's Medical Center (US)
- University Health Network (CA)
- Children's Hospital of Philadelphia (US)
- Children's Hospital of Los Angeles (US)
- Princess Margaret Cancer Centre (CA)
- University of Pennsylvania (US)
- The University of Texas Southwestern Medical Center (US)
Publication Details
- Journal
- Pediatric Blood & Cancer
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1002/pbc.31852
- Citations
- 1
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- U.S. Department of Defense
- Alex's Lemonade Stand Foundation for Childhood Cancer
- Cancer Prevention and Research Institute of Texas
- University of Texas Southwestern Medical Center
- Pablove Foundation
- National Institutes of Health
- University of Texas MD Anderson Cancer Center
- National Cancer Institute