Respiratory symptoms associated with a new lobe-based bronchial scoring system in an urban Chinese low-dose CT screening population
Question Bronchiectasis is frequently detected on low-dose CT lung cancer screening. However, a lob-based bronchial scoring, its clinical relevance and association with respiratory symptoms are lacking. Findings Over 40% of participants had bronchiectasis, mostly in the lower lobes. Higher bronchial scores were associated with increased wheeze risk and reduced chest pain. Clinical relevance Early detection of bronchiectasis through CT-based scoring in lung cancer screening can improve assessment of respiratory health, enabling timely interventions and potentially reducing disease progression. Future research should explore the clinical implications of our new bronchial scoring system.
Authors
- Maaike de Vries (ORCID: https://orcid.org/0000-0001-7210-8174)
- Rozemarijn Vliegenthart (ORCID: https://orcid.org/0000-0002-7262-3376)
- Zhenhui Nie (ORCID: https://orcid.org/0009-0002-7825-4871)
- Monique D. Dorrius (ORCID: https://orcid.org/0000-0001-9825-6001)
- Dirk‐Jan Slebos (ORCID: https://orcid.org/0000-0001-9555-3422)
- Geertruida H. de Bock (ORCID: https://orcid.org/0000-0003-3104-4471)
- Matthijs Oudkerk (ORCID: https://orcid.org/0000-0003-2800-4110)
- Zhaoxiang Ye (ORCID: https://orcid.org/0000-0003-3157-8393)
- Xiaofei Yang (ORCID: https://orcid.org/0000-0003-4876-1880)
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Tianjin Medical University Cancer Institute and Hospital (CN)
Publication Details
- Journal
- European Radiology
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1007/s00330-025-11712-z
- Citations
- 2
- Primary Topic
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Type
- article
- Field-Weighted Citation Impact
- 3.04
Funders
- Koninklijke Nederlandse Akademie van Wetenschappen
- Ministry of Science and Technology of the People's Republic of China
- China Scholarship Council
- Tianjin Medical University
- Cancer Institute and Hospital, Chinese Academy of Medical Sciences