Abstract 2210 Inkjet Dispenser-Liquid Vortex Capture-Mass Spectrometry for Single-Cell Metabolomics in Hep G2 Steatosis Caused by Tamoxifen

Exploring cellular biology at single-cell resolution using genomics and transcriptomics is revolutionizing the study of metabolic pathways and the identification of therapeutic targets within heterogeneous cell populations. Unlike bulk measurements, single-cell analyses reveal pathways that were previously obscured, enabling advancements in medicine, cellular manufacturing, and bioengineering. However, solely genomic approaches may provide an incomplete understanding of biochemical pathways and therapeutic target behavior under treatment.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109425
Primary Topic
Metabolomics and Mass Spectrometry Studies
Type
article
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article

Abstract 2210 Inkjet Dispenser-Liquid Vortex Capture-Mass Spectrometry for Single-Cell Metabolomics in Hep G2 Steatosis Caused by Tamoxifen

John F. Cahill, Stephen Zambrzycki, Vilmos Kertész
Journal of Biological Chemistry
Metabolomics and Mass Spectrometry Studies
article

Abstract 2210 Inkjet Dispenser-Liquid Vortex Capture-Mass Spectrometry for Single-Cell Metabolomics in Hep G2 Steatosis Caused by Tamoxifen

John F. Cahill, Stephen Zambrzycki, Vilmos Kertész
article en

Abstract

Exploring cellular biology at single-cell resolution using genomics and transcriptomics is revolutionizing the study of metabolic pathways and the identification of therapeutic targets within heterogeneous cell populations. Unlike bulk measurements, single-cell analyses reveal pathways that were previously obscured, enabling advancements in medicine, cellular manufacturing, and bioengineering. However, solely genomic approaches may provide an incomplete understanding of biochemical pathways and therapeutic target behavior under treatment.

Journal of Biological ChemistryVol. 301(5)
Case Western Reserve University (US)
Affordable and clean energy
Openalex Percentile: Top 88%
Metabolomics and Mass Spectrometry Studies
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