Abstract 1761 Microbial Degradation of Cyanoguanidine

Anthropogenic biguanide compounds are widely used in agriculture, industry, and medicine, making them prevalent in the environment. The extensive use of compounds like cyanoguanidine, guanylurea, and metformin has led to their accumulation as pollutants in waterways. This research focused on the microbial degradation of cyanoguanidine, a common biguanide compound used as an additive in agricultural products and frequently present as an impurity in the production of pharmaceuticals such as metformin.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109620
Primary Topic
Metabolism and Genetic Disorders
Type
article
Field-Weighted Citation Impact
0.00

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article

Abstract 1761 Microbial Degradation of Cyanoguanidine

Larry Wackett, Hanan Abdi, Betsy M. Martínez-Vaz, Sophia Schlink
Journal of Biological Chemistry
Metabolism and Genetic Disorders
article

Abstract 1761 Microbial Degradation of Cyanoguanidine

Larry Wackett, Hanan Abdi, Betsy M. Martínez-Vaz, Sophia Schlink
article en

Abstract

Anthropogenic biguanide compounds are widely used in agriculture, industry, and medicine, making them prevalent in the environment. The extensive use of compounds like cyanoguanidine, guanylurea, and metformin has led to their accumulation as pollutants in waterways. This research focused on the microbial degradation of cyanoguanidine, a common biguanide compound used as an additive in agricultural products and frequently present as an impurity in the production of pharmaceuticals such as metformin.

Journal of Biological ChemistryVol. 301(5)
Hamline University (US)
National Science Foundation
Zero hunger
Openalex Percentile: Top 84%
Metabolism and Genetic Disorders
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