Abstract 1874 Exploring the Role of catp-6 at the C. elegans Neuromuscular Junction

Acetylcholine (ACh) is responsible for muscle contraction when it binds to nicotinic acetylcholine receptors (nAChRs) at the neuromuscular junction (NMJ). While the NMJ is largely studied for its key role in locomotion, there remains much to be discovered. The roundworm C. elegans is an excellent model for studying genes involved in neuromuscular function due to its well-studied circuitry and genome. In C. elegans, the loss of the gene catp-6 has been associated with defects in movement and locomotion.