Abstract 1294 Studies of metabolism in an oomycete reveal atypical compartmentalization of glycolytic and amino acid biosynthesis pathways and biochemical redundancies resulting from horizontal gene transfer
Oomycetes are a group of filamentous eukaryotes in the clade Stramenopila, and include some of the world's most notorious and destructive plant pathogens. Oomycetes possess a number of non-canonical metabolic pathways compared to traditional model systems, and many of the enzymes in these unusual pathways are thought to have been acquired by horizontal or endosymbiotic gene transfer. These novelties have been proposed to contribute to the evolutionary success of oomycetes; however, their functional significance has remained untested.
Authors
- Howard S. Judelson (ORCID: https://orcid.org/0000-0001-7865-6235)
- Carl Mendoza
Institutions
- University of California, Riverside (US)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jbc.2025.109469
- Primary Topic
- Microbial Metabolic Engineering and Bioproduction
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Science Foundation
- U.S. Department of Agriculture
- National Institute of Food and Agriculture