Abstract 1294 Studies of metabolism in an oomycete reveal atypical compartmentalization of glycolytic and amino acid biosynthesis pathways and biochemical redundancies resulting from horizontal gene transfer

Oomycetes are a group of filamentous eukaryotes in the clade Stramenopila, and include some of the world's most notorious and destructive plant pathogens. Oomycetes possess a number of non-canonical metabolic pathways compared to traditional model systems, and many of the enzymes in these unusual pathways are thought to have been acquired by horizontal or endosymbiotic gene transfer. These novelties have been proposed to contribute to the evolutionary success of oomycetes; however, their functional significance has remained untested.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109469
Primary Topic
Microbial Metabolic Engineering and Bioproduction
Type
article
Field-Weighted Citation Impact
0.00

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Abstract 1294 Studies of metabolism in an oomycete reveal atypical compartmentalization of glycolytic and amino acid biosynthesis pathways and biochemical redundancies resulting from horizontal gene transfer

Howard S. Judelson, Carl Mendoza
Journal of Biological Chemistry
Microbial Metabolic Engineering and Bioproduction
article

Abstract 1294 Studies of metabolism in an oomycete reveal atypical compartmentalization of glycolytic and amino acid biosynthesis pathways and biochemical redundancies resulting from horizontal gene transfer

Howard S. Judelson, Carl Mendoza
article en

Abstract

Oomycetes are a group of filamentous eukaryotes in the clade Stramenopila, and include some of the world's most notorious and destructive plant pathogens. Oomycetes possess a number of non-canonical metabolic pathways compared to traditional model systems, and many of the enzymes in these unusual pathways are thought to have been acquired by horizontal or endosymbiotic gene transfer. These novelties have been proposed to contribute to the evolutionary success of oomycetes; however, their functional significance has remained untested.

Journal of Biological ChemistryVol. 301(5)
University of California, Riverside (US)
National Science Foundation, U.S. Department of Agriculture, National Institute of Food and Agriculture
Zero hunger
Openalex Percentile: Top 88%
Microbial Metabolic Engineering and Bioproduction
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