Abstract 2220 Utilizing the cuoA promoter to examine arginine kinase's role in Myxococcus xanthus starvation-induced sporulation

Myxococcus xanthus is a predatory soil bacterium with a complex life cycle. When subjected to stress, this normally motile bacteria forms specialized mounds called “fruiting bodies” that contain spores. We recently discovered that M. xanthus possesses a horizontally transferred gene encoding arginine kinase (AK), a protein that catalyzes the phosphorylation of l-arginine into phosphoarginine in other systems and had an unexpected role in this process. AKs are generally involved in energy homeostasis in other eukaryotic organisms.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109643
Primary Topic
Cancer Research and Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Abstract 2220 Utilizing the cuoA promoter to examine arginine kinase's role in Myxococcus xanthus starvation-induced sporulation

Dean Fraga, Brian Praul
Journal of Biological Chemistry
Cancer Research and Treatments
article

Abstract 2220 Utilizing the cuoA promoter to examine arginine kinase's role in Myxococcus xanthus starvation-induced sporulation

Dean Fraga, Brian Praul
article en

Abstract

Myxococcus xanthus is a predatory soil bacterium with a complex life cycle. When subjected to stress, this normally motile bacteria forms specialized mounds called “fruiting bodies” that contain spores. We recently discovered that M. xanthus possesses a horizontally transferred gene encoding arginine kinase (AK), a protein that catalyzes the phosphorylation of l-arginine into phosphoarginine in other systems and had an unexpected role in this process. AKs are generally involved in energy homeostasis in other eukaryotic organisms.

Journal of Biological ChemistryVol. 301(5)
Zero hunger
Openalex Percentile: Top 84%
Cancer Research and Treatments
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