Abstract 1277 Blood levels of glucagon like 1 peptide in the course of acute myocardial in patients: A possible clinical significance

Introduction: Ischemic heart disease is the most killing disease worldwide. Glucagon like1 peptide (GL1P) is a 30 amino acids incretin gut derived peptide hormone with numerous physiological actions. Several experimental evidence suggests it may sustain or hold cardiomyocytes at viable level. It has been shown to reduced size of ischemic zone in rat heart after myocardial ischemia/reperfusion [1, 2, 3]. Objective: The aim of the study was to determine the time course of GL1P levels in the plasma of MI patients over 12 hours compared to healthy individuals as control.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109023
Primary Topic
Diabetes Treatment and Management
Type
article
Field-Weighted Citation Impact
0.00

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Abstract 1277 Blood levels of glucagon like 1 peptide in the course of acute myocardial in patients: A possible clinical significance

Tala Jaradat, Said Y. Khatib, Anas Alshannag, Osama Dweikat et al.
Journal of Biological Chemistry
Diabetes Treatment and Management
article

Abstract 1277 Blood levels of glucagon like 1 peptide in the course of acute myocardial in patients: A possible clinical significance

Tala Jaradat, Said Y. Khatib, Anas Alshannag, Osama Dweikat, Husam Askeri
article en

Abstract

Introduction: Ischemic heart disease is the most killing disease worldwide. Glucagon like1 peptide (GL1P) is a 30 amino acids incretin gut derived peptide hormone with numerous physiological actions. Several experimental evidence suggests it may sustain or hold cardiomyocytes at viable level. It has been shown to reduced size of ischemic zone in rat heart after myocardial ischemia/reperfusion [1, 2, 3]. Objective: The aim of the study was to determine the time course of GL1P levels in the plasma of MI patients over 12 hours compared to healthy individuals as control.

Journal of Biological ChemistryVol. 301(5)
U.S. Department of Energy
Good health and well-being
Openalex Percentile: Top 81%
Diabetes Treatment and Management
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