Abstract 2823 Identification of potential GALNTs in microinvertebrates using a novel predictive HMM

Protein glycosylation, a type of protein post-translational modification, in which a monosaccharide is bound to protein by a glycosidic linkage. These modifications are commonly seen in animals, plants and microorganisms. One of these protein glycosylation mechanisms is the O-linked N-acetylgalactosamine (GalNAc). This modification alters a galactose molecule for it to bind serine and threonine residues. Once GalNAc is added to Ser/Thr, additional glycans can be attached, ultimately forming complex glycoproteins.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109343
Primary Topic
Molecular Biology Techniques and Applications
Type
article
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article

Abstract 2823 Identification of potential GALNTs in microinvertebrates using a novel predictive HMM

Ramiro González Garza, Jonathon E. Mohl
Journal of Biological Chemistry
Molecular Biology Techniques and Applications
article

Abstract 2823 Identification of potential GALNTs in microinvertebrates using a novel predictive HMM

Ramiro González Garza, Jonathon E. Mohl
article en

Abstract

Protein glycosylation, a type of protein post-translational modification, in which a monosaccharide is bound to protein by a glycosidic linkage. These modifications are commonly seen in animals, plants and microorganisms. One of these protein glycosylation mechanisms is the O-linked N-acetylgalactosamine (GalNAc). This modification alters a galactose molecule for it to bind serine and threonine residues. Once GalNAc is added to Ser/Thr, additional glycans can be attached, ultimately forming complex glycoproteins.

Journal of Biological ChemistryVol. 301(5)
The University of Texas at El Paso (US)
Openalex Percentile: Top 88%
Molecular Biology Techniques and Applications
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