Abstract 1320 Regulation of mitochondrial health during tissue regeneration

a hallmark of aging and common human diseases, and the mechanisms by which tissues accomodate dysfunctional organelles are under intense investigation.We discuss here the consequences of mitochondrial electron transport chain dysfunction in stem cell populations, in order to understand how tissues promote the regeneration of healthy tissue and unearth strategies to combat accumulating mitochondrial damage during an organism's lifespan.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109470
Primary Topic
Mitochondrial Function and Pathology
Type
article
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article

Abstract 1320 Regulation of mitochondrial health during tissue regeneration

Prashant Mishra
Journal of Biological Chemistry
Mitochondrial Function and Pathology
article

Abstract 1320 Regulation of mitochondrial health during tissue regeneration

Prashant Mishra
article en

Abstract

a hallmark of aging and common human diseases, and the mechanisms by which tissues accomodate dysfunctional organelles are under intense investigation.We discuss here the consequences of mitochondrial electron transport chain dysfunction in stem cell populations, in order to understand how tissues promote the regeneration of healthy tissue and unearth strategies to combat accumulating mitochondrial damage during an organism's lifespan.

Journal of Biological ChemistryVol. 301(5)
Southwestern Medical Center (US), The University of Texas Southwestern Medical Center (US)
Zero hunger
Openalex Percentile: Top 88%
Mitochondrial Function and Pathology
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