Abstract 1171 PODIOMICS: Biomarkers for Prediction, Prognosis and Treatment of (non)Healing Chronic Diabetic Foot Ulcers

Diabetic foot ulcers (DFUs) are a major and potentially life-threatening complication of diabetes mellitus. The objective is to detect and treat the 25 million people in North America (1/4 of diabetics) with DFUs exhibiting significant impaired healing mechanisms due to cellular and biochemical processes involved in the injury and inflammatory response. The four phases of wound healing are inflammation, migration, proliferation, and remodeling. Acute wounds progress through these stages systematically but in chronic wounds, healing is “frozen” at the inflammation stage.