One‐Pot Tandem Alkylsulfonylation/Cyclization of Unactivated Alkenes to Construct Alkylsulfonyl‐Containing Polycyclic Quinazolinones Under Photocatalysis
Abstract Visible‐light photoredox‐catalyzed one‐pot tandem alkylsulfonylation/cyclization of unactivated alkenes to construct alkylsulfonyl‐containing polycyclic quinazolinones from 4‐alkyl Hantzsch esters, DABCO(SO 2 ) 2 and N‐alkene‐tethered quinazolinones has been accomplished. This mild transformation accommodates diversely decorated substrates, affords the target products in 69–90% yields, and can be readily scaled up. The efficacy of the current catalysis arises from the use of tetrabutylammonium decatungstate as the photocatalyst and cheap K 2 S 2 O 8 as the oxidant.
Authors
- Yang Shi (ORCID: https://orcid.org/0000-0002-7185-0972)
- Rong Huang (ORCID: https://orcid.org/0000-0003-2810-4269)
- Zhen Yao (ORCID: https://orcid.org/0000-0003-0408-6801)
- Lijin Xu (ORCID: https://orcid.org/0000-0003-4067-8898)
- Ying Zhou (ORCID: https://orcid.org/0000-0002-7661-5568)
- Huabin Wang (ORCID: https://orcid.org/0000-0001-5938-5409)
- Xiongwei Liu (ORCID: https://orcid.org/0000-0002-9005-260X)
- Bo‐Wen Pan (ORCID: https://orcid.org/0000-0003-0930-4492)
- Jing Guan (ORCID: https://orcid.org/0009-0007-0535-6195)
Institutions
- Guizhou University (CN)
- Renmin University of China (CN)
Publication Details
- Journal
- Asian Journal of Organic Chemistry
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1002/ajoc.202500341
- Citations
- 1
- Primary Topic
- Sulfur-Based Synthesis Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.94