Abstract 2753 Proteomic Insights into the Physiology of Ixodes ricinus Ticks

characteristics in healthy cells and enhancement of hallmarks in transformed cells, with lower expression associated with worse survival rates in early-stage breast cancer patients.Cadmium can inhibit the interaction of LLPS proteins with RNA or DNA molecules, affecting cellular processes such as mRNA processing and chromatin organization, resulting in a topological rearrangement at the nucleolus level and other condensates that induce global chromatin silencing, in turn promoting the expression of oncogenes.Additional reports demonstrate that low expression of FUS, for example, increases the proliferation and migration of prostate and liver cancer cells, respectively, and its overexpression confers tumor-suppressing capabilities by inhibiting invasion and pluripotency.Additionally, it has been reported that high exposure to divalent cations alters the formation of RNA coacervates.However, within the context of exosomes, little has been demonstrated about the effect of heavy metals on the alteration of condensates and their relationship with tumorigenesis.