Abstract 2806 Structural Analysis of the Hazara Virus RNA Promoter

The Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is a tick-borne virus capable of tick-human, tick-livestock, human-human and livestock-human vectored transmission. CCHFV is endemic throughout the Middle East, Southeast Europe, Africa and various regions within Asia with regions of potential infectivity spreading as global warming makes colder regions habitable for the hyalomma tick. This virus is of particular importance to the United States Military due to its high mortality rates (10-40%), lack of effective therapeutics, and prevalence in regions of military importance.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109786
Primary Topic
Viral Infections and Vectors
Type
article
Field-Weighted Citation Impact
0.00
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article

Abstract 2806 Structural Analysis of the Hazara Virus RNA Promoter

Ina P. O’Carroll, Richard Carter
Journal of Biological Chemistry
Viral Infections and Vectors
article

Abstract 2806 Structural Analysis of the Hazara Virus RNA Promoter

Ina P. O’Carroll, Richard Carter
article en

Abstract

The Crimean-Congo Haemorrhagic Fever Virus (CCHFV) is a tick-borne virus capable of tick-human, tick-livestock, human-human and livestock-human vectored transmission. CCHFV is endemic throughout the Middle East, Southeast Europe, Africa and various regions within Asia with regions of potential infectivity spreading as global warming makes colder regions habitable for the hyalomma tick. This virus is of particular importance to the United States Military due to its high mortality rates (10-40%), lack of effective therapeutics, and prevalence in regions of military importance.

Journal of Biological ChemistryVol. 301(5)
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Viral Infections and Vectors
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