Abstract 1531 Exploring Pesticide Effects on Hematopoiesis and the Thymus

Hematopoiesis in the bone marrow (BM) produces red blood cells, platelets, or various white blood cells. Common lymphocyte progenitors in the BM can migrate to the thymus to form T lymphocytes, a type of immune cell. In some cases, bone marrow failure (BMF) arises from impairments in hematopoiesis and results in the inability to produce necessary blood cells. California's Central Valley has a high exposure to pesticides due to agriculture, but surprisingly, there has been little published research regarding the direct effects of pesticides on BMF.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109350
Primary Topic
Immunotoxicology and immune responses
Type
article
Field-Weighted Citation Impact
0.00

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article

Abstract 1531 Exploring Pesticide Effects on Hematopoiesis and the Thymus

J. Michael Young, Jennifer O. Manilay
Journal of Biological Chemistry
Immunotoxicology and immune responses
article

Abstract 1531 Exploring Pesticide Effects on Hematopoiesis and the Thymus

J. Michael Young, Jennifer O. Manilay
article en

Abstract

Hematopoiesis in the bone marrow (BM) produces red blood cells, platelets, or various white blood cells. Common lymphocyte progenitors in the BM can migrate to the thymus to form T lymphocytes, a type of immune cell. In some cases, bone marrow failure (BMF) arises from impairments in hematopoiesis and results in the inability to produce necessary blood cells. California's Central Valley has a high exposure to pesticides due to agriculture, but surprisingly, there has been little published research regarding the direct effects of pesticides on BMF.

Journal of Biological ChemistryVol. 301(5)
University of California, Merced (US)
National Institutes of Health
Zero hunger
Openalex Percentile: Top 85%
Immunotoxicology and immune responses
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