Dynamics of mitochondrial DNA copy number regulation in relation to gastric cancer survival
Higher mtDNA-CN in peripheral is correlated with the shorter overall survival in gastric cancer patient. Higher expression of MYO15A, OSGEP, and CDK10 is associated with shorter survival in gastric cancer patients, potentially by regulating mtDNA-CN, suggesting potential targets for future therapeutic interventions of gastric cancer.
Authors
- Zhengguo Ji (ORCID: https://orcid.org/0000-0001-8269-5958)
- Qichang Yang (ORCID: https://orcid.org/0000-0003-3657-7023)
- Haihong Ye (ORCID: https://orcid.org/0000-0001-7282-6280)
- Tian Zhao (ORCID: https://orcid.org/0009-0005-6742-4363)
- Yuying Han
Institutions
- Capital Medical University (CN)
Publication Details
- Journal
- Discover Oncology
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1007/s12672-025-02825-4
- Citations
- 1
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.81
Funders
- National Natural Science Foundation of China