Abstract 2507 Finding an RNA Aptamer Against SOD-1 to be Used as a Therapeutic for ALS Patients

Amyotrophic Lateral Sclerosis (ALS) diagnoses are terminal. There are only 7 drugs that treat ALS, most of which only improve life expectancy by a few months (ALS Association). Diagnoses are on the rise, and current treatments do little to extend life, creating a dire forecast that punctuates the need for effective ALS treatments. This neurodegenerative disease affects approximately 200,000 people globally (ALS Society of Canada) and cases are predicted to increase by 69% between 2015 and 2040 (Nature Communications).

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109781
Primary Topic
Amyotrophic Lateral Sclerosis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Abstract 2507 Finding an RNA Aptamer Against SOD-1 to be Used as a Therapeutic for ALS Patients

Avery Matthews, Gwendolyn M. Stovall
Journal of Biological Chemistry
Amyotrophic Lateral Sclerosis Research
article

Abstract 2507 Finding an RNA Aptamer Against SOD-1 to be Used as a Therapeutic for ALS Patients

Avery Matthews, Gwendolyn M. Stovall
article en

Abstract

Amyotrophic Lateral Sclerosis (ALS) diagnoses are terminal. There are only 7 drugs that treat ALS, most of which only improve life expectancy by a few months (ALS Association). Diagnoses are on the rise, and current treatments do little to extend life, creating a dire forecast that punctuates the need for effective ALS treatments. This neurodegenerative disease affects approximately 200,000 people globally (ALS Society of Canada) and cases are predicted to increase by 69% between 2015 and 2040 (Nature Communications).

Journal of Biological ChemistryVol. 301(5)
The University of Texas at Austin (US)
Zero hunger
Openalex Percentile: Top 79%
Amyotrophic Lateral Sclerosis Research
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