Abstract 1118 A logistic regression model predicts oscillation regimes in the MinDE reaction diffusion system

A critical characteristic of life is its ability to organize itself in space and time. At the single-cell level, proteins and metabolites undergo constant dynamic organization to facilitate even the simplest processes. The bacterial MinDE proteins are a minimal reaction-diffusion system that produce oscillating waves when transformed into eukaryotic cells. Previous work has used MinDE as a platform for synthetic spatiotemporal circuit design. However, these circuits are restricted by the expression regimes that allow oscillation.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.110146
Primary Topic
Electron Spin Resonance Studies
Type
article
Field-Weighted Citation Impact
0.00

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Abstract 1118 A logistic regression model predicts oscillation regimes in the MinDE reaction diffusion system

Thomas Galateo, Scott M. Coyle, Elliott W. Z. Weix, R. Rajasekaran et al.
Journal of Biological Chemistry
Electron Spin Resonance Studies
article

Abstract 1118 A logistic regression model predicts oscillation regimes in the MinDE reaction diffusion system

Thomas Galateo, Scott M. Coyle, Elliott W. Z. Weix, R. Rajasekaran, Dennis T. Bolshakov
article en

Abstract

A critical characteristic of life is its ability to organize itself in space and time. At the single-cell level, proteins and metabolites undergo constant dynamic organization to facilitate even the simplest processes. The bacterial MinDE proteins are a minimal reaction-diffusion system that produce oscillating waves when transformed into eukaryotic cells. Previous work has used MinDE as a platform for synthetic spatiotemporal circuit design. However, these circuits are restricted by the expression regimes that allow oscillation.

Journal of Biological ChemistryVol. 301(5)
Los Alamos National Laboratory (US)
National Institutes of Health
Climate action
Openalex Percentile: Top 90%
Electron Spin Resonance Studies
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