Abstract 1966 Urban Air Pollution Impairs Lung Redox Homeostasis and Inflammatory Response, Hindering Tissue Recovery
Air pollution is acknowledged as a significant risk factor for chronic non-communicable diseases, impacting global morbidity and mortality. Breathing polluted air leads to pulmonary oxidative stress, initiating, in turn, inflammatory pathways. We aimed to study the effects of the particulate matter present in urban air on pulmonary tissue damage and its repair ability focusing on the combination of oxidative stress and inflammation. BALB/c mice were exposed to filtered air (FA) or urban air (UA) from Buenos Aires City, in whole-body exposure chambers for 8 weeks.
Authors
- Agustina Freire (ORCID: https://orcid.org/0009-0006-1469-3794)
- Laura Caltana (ORCID: https://orcid.org/0000-0001-5301-4922)
- Valeria Trípodi
- Sofía Reynoso (ORCID: https://orcid.org/0000-0002-5349-5444)
- Pablo Evelson (ORCID: https://orcid.org/0000-0001-7920-7968)
- Natalia Magnani (ORCID: https://orcid.org/0000-0001-8394-5277)
- Mariana Garcés (ORCID: https://orcid.org/0000-0001-8378-9614)
- Manuela Martinefski (ORCID: https://orcid.org/0000-0002-4501-3783)
- Florencia Sarno
Institutions
- Universidad de Buenos Aires (AR)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jbc.2025.110110
- Primary Topic
- Air Quality and Health Impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Arizona State University