Abstract 1141 A blueprint for biomolecular condensation driven by bacterial microcompartment encapsulation peptides

Bacteria are increasingly appreciated to exert spatiotemporal control over their cytoplasm with “organelles”. For example, bacterial microcompartments (BMC) are structurally conserved protein polyhedra which encase functionally diverse enzymatic “cargo” within a shell boundary, thereby sequestering inter-related aspects of cellular metabolism (catabolic or anabolic). As we understand more about BMCs, leveraging the ability to package functionally diverse cargoes within a modular chassis will make them targets for bioengineering efforts.