Abstract 2206 Assessment of STARD6 SNPs Associated with Alzheimer's Disease

Alzheimer's Disease (AD) is a degenerative brain disorder that causes symptoms such as depression and memory problems due to changes in beta-amyloid and tau proteins in the brain. However, there is very little known regarding the molecular mechanisms that occur early in the progression of this disease. Recent genetic studies have linked StarD6 with AD risk. The StarD6 protein is expressed in the testis, ovaries, and brain regions such as the hippocampal formation, which is where degeneration of the brain begins in the progression of AD.