Abstract 1273 Hepatoprotective antioxidant effect of the ethanolic fraction of the ethanolic extract of Justicia spicigera in a non-alcoholic fatty liver model
Fatty liver disease is associated with metabolic risk factors such as obesity, type 2 diabetes mellitus, dyslipidemia and metabolic syndrome. In parallel, it is estimated that 30% of patients with non-alcoholic fatty liver disease (NAFLD) may develop complications such as non-alcoholic steatohepatitis (NASH) at the time of detection. Likewise, 38% of patients with NAFLD and development of fibrosis may develop cirrhosis, which doubles the possibility of suffering from hepatocellular carcinoma (HCC).
Authors
- Marina Murillo‐Villicaña
- Cinthia Landa‐Moreno
- Rafael Salgado‐Garciglia (ORCID: https://orcid.org/0000-0001-5920-6562)
- Asdrúbal Aguilera‐Méndez (ORCID: https://orcid.org/0000-0003-0326-2068)
- Jenaro Lemus‐de la Cruz (ORCID: https://orcid.org/0000-0002-3020-7083)
- Alfredo Saavedra‐Molina (ORCID: https://orcid.org/0000-0002-0811-2950)
- María J. Rosales
- Mayra Murillo-Villicaña
- Fernanda Mejía-Peña
Institutions
- Universidad Michoacana de San Nicolás de Hidalgo (MX)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jbc.2025.109467
- Primary Topic
- Drug-Induced Hepatotoxicity and Protection
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad Michoacana de San Nicolás de Hidalgo