Abstract 2733 Gut Commensal Metabolites Modulate V. cholerae Biofilm Growth

Microbes living in the human gut engage in complex interactions which result in the protection of their host against pathogens. One such pathogen, Vibrio cholerae, infects the intestine and uses motility and biofilm formation as important virulence factors. Previously, our lab identified Enterocloster citroniae as a gut microbiota member that produces metabolites with a dampening effect on V. cholerae motility while increasing biofilm formation. This reflects an expected inverse relationship between motility and biofilm formation in bacterial behavior.