Abstract 2042 Characterization of TonB4 and TonB6 Proteins in Bacteroides thetaiotaomicron through generation of multiple gene deletion strains

Bacteroides are vital members of the human gut microbial community that are primarily responsible for the utilization of polysaccharides. Bacteroides thetaiotaomicron (B. theta) is a model organism for the Bacteroides genus and transport of degraded oligosaccharides through TonB-dependent transporters (TBDT). These outer membrane transporters are powered by an inner membrane energizing complex composed of the TonB, ExbB, and ExbD proteins. Previous research has identified 11 homologous TonB proteins encoded in the B.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109635
Primary Topic
Plant-based Medicinal Research
Type
article
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Abstract 2042 Characterization of TonB4 and TonB6 Proteins in Bacteroides thetaiotaomicron through generation of multiple gene deletion strains

Rebecca M. Pollet, Nisrine Jabara, Kalina Rashkov
Journal of Biological Chemistry
Plant-based Medicinal Research
article

Abstract 2042 Characterization of TonB4 and TonB6 Proteins in Bacteroides thetaiotaomicron through generation of multiple gene deletion strains

Rebecca M. Pollet, Nisrine Jabara, Kalina Rashkov
article en

Abstract

Bacteroides are vital members of the human gut microbial community that are primarily responsible for the utilization of polysaccharides. Bacteroides thetaiotaomicron (B. theta) is a model organism for the Bacteroides genus and transport of degraded oligosaccharides through TonB-dependent transporters (TBDT). These outer membrane transporters are powered by an inner membrane energizing complex composed of the TonB, ExbB, and ExbD proteins. Previous research has identified 11 homologous TonB proteins encoded in the B.

Journal of Biological ChemistryVol. 301(5)
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Plant-based Medicinal Research
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