A Post-Quantum Blockchain and Autonomous AI-Enabled Scheme for Secure Healthcare Information Exchange

Secure healthcare information exchange (HIE) is critical to improving medical services, enabling data interoperability, and ensuring patient privacy. However, the increasing threat posed by quantum computing challenges the reliability of conventional cryptographic mechanisms. To address this, we propose a post-quantum secure healthcare data-sharing scheme that combines the Extended Merkle Signature Scheme (XMSS) and consortium blockchain technology to guarantee the integrity, authenticity, and traceability of electronic medical records (EMRs). Furthermore, the scheme incorporates autonomous artificial intelligence (AI) to assist healthcare professionals in generating accurate and intelligent diagnostic reports, enhancing clinical decision-making. We theoretically analyze the scheme's security in the random oracle model, demonstrating that it effectively resists various threats. Performance evaluation shows that the scheme is particularly suitable for HIE scenarios as it reduces about 49% in total computational overheads and 36% in blockchain storage compared to other schemes.

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Publication Details

Journal
IEEE Journal of Biomedical and Health Informatics
Published
2025-06-13
DOI
https://doi.org/10.1109/jbhi.2025.3579722
Citations
4
Primary Topic
Blockchain Technology Applications and Security
Type
article
Field-Weighted Citation Impact
12.98
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article

A Post-Quantum Blockchain and Autonomous AI-Enabled Scheme for Secure Healthcare Information Exchange

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Blockchain Technology Applications and Security
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article

A Post-Quantum Blockchain and Autonomous AI-Enabled Scheme for Secure Healthcare Information Exchange

Yuyuan Liu, Shuanggen Liu, Kexin Tian, Xiuhua Lu, S. N. Tirumala Rao, Jue Wang, Linlin He
article en
4 citations

Abstract

Secure healthcare information exchange (HIE) is critical to improving medical services, enabling data interoperability, and ensuring patient privacy. However, the increasing threat posed by quantum computing challenges the reliability of conventional cryptographic mechanisms. To address this, we propose a post-quantum secure healthcare data-sharing scheme that combines the Extended Merkle Signature Scheme (XMSS) and consortium blockchain technology to guarantee the integrity, authenticity, and traceability of electronic medical records (EMRs). Furthermore, the scheme incorporates autonomous artificial intelligence (AI) to assist healthcare professionals in generating accurate and intelligent diagnostic reports, enhancing clinical decision-making. We theoretically analyze the scheme's security in the random oracle model, demonstrating that it effectively resists various threats. Performance evaluation shows that the scheme is particularly suitable for HIE scenarios as it reduces about 49% in total computational overheads and 36% in blockchain storage compared to other schemes.

IEEE Journal of Biomedical and Health InformaticsVol. 29(9)
Qufu Normal University (CN), East China University of Technology (CN), Xi’an University of Posts and Telecommunications (CN)
Openalex Percentile: Top 2%
Blockchain Technology Applications and Security
12.98
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A Post-Quantum Blockchain and Autonomous AI-Enabled Scheme for Secure Healthcare Information Exchange — Yuyuan Liu, Shuanggen Liu, et al. · IEEE Journal of Biomedical and Health Informatics (2025) | TGRS Research Map | TGRS