Fermented Morinda citrifolia extract improves late-onset hypogonadism in aged rats
FME alleviated LOH-related symptoms in aged rats by modulating testosterone metabolism, enhancing reproductive and physical health, and maintaining a favorable safety profile. These findings validate the in vivo efficacy of FME and highlight its potential as a natural therapeutic candidate for managing LOH and related conditions.
Authors
- Yangsoo Jang (ORCID: https://orcid.org/0000-0002-2169-3112)
- Keum Seok Bae (ORCID: https://orcid.org/0000-0003-4728-3047)
- Se‐Young Choung (ORCID: https://orcid.org/0000-0001-7619-6263)
- Hyesung Lee (ORCID: https://orcid.org/0009-0008-0720-9743)
- Do Sik Min (ORCID: https://orcid.org/0000-0002-8570-5098)
- Eun-Min Kim (ORCID: https://orcid.org/0009-0003-8739-5526)
- Hee‐Yeon Kwon
- Tae Hyun Kim (ORCID: https://orcid.org/0000-0002-0154-518X)
- Ji‐Soo Choi (ORCID: https://orcid.org/0009-0008-5535-4144)
- Seong Hun Lim
- Jae-Yeon Lee (ORCID: https://orcid.org/0000-0002-2073-850X)
Institutions
- Incheon National University (KR)
- Pohang Iron and Steel (South Korea) (KR)
- Inha University (KR)
- Yonsei University (KR)
- Dankook University (KR)
Publication Details
- Journal
- Biomedicine & Pharmacotherapy
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1016/j.biopha.2025.118256
- Citations
- 2
- Primary Topic
- Morinda citrifolia extract uses
- Type
- article
- Field-Weighted Citation Impact
- 4.76