Successful transbronchial cryobiopsy of a ground glass opacity predominant lesion assisted with a 3-dimensional mobile C-arm system under moderate sedation

The usefulness of a 3-dimensional (3D) mobile C-arm system under moderate sedation is little known. A 76-year-old man was referred to our hospital due to a ground-glass opacity (GGO) predominant pulmonary nodule. No obvious changes in tumor exposure were observed in direct visualization using ultra-thin bronchoscopy under moderate sedation. We could confirm the tool-in-lesion using real-time 3D imaging using a 3D mobile C-arm system, and successfully diagnosed a papillary adenocarcinoma by a cryobiopsy. The 3D mobile C-arm system has the potential to provide valuable real-time guidance for transbronchial biopsies of GGO-predominant small lesions even under moderate sedation.