Nano-encapsulated ferulic acid in sesame protein isolate alleviates acrylamide-induced liver toxicity and genotoxicity in rats via oxidative stress and DNA damage modulation
Both encapsulated forms, especially the nanoform, significantly mitigated liver toxicity. These findings underscore their potential as effective natural therapies for liver damage caused by ACR, and supporting liver health.
Authors
- Engy M. Akl (ORCID: https://orcid.org/0000-0003-3727-2758)
- Elham Ahmed (ORCID: https://orcid.org/0000-0001-5019-8607)
- Hend A. Essa (ORCID: https://orcid.org/0000-0002-5108-1395)
- Fatma El Zahraa Abd EL Hakam
Institutions
- Al-Azhar University (EG)
- National Research Centre (EG)
Publication Details
- Journal
- BMC Pharmacology and Toxicology
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1186/s40360-025-00946-8
- Citations
- 4
- Primary Topic
- Sesame and Sesamin Research
- Type
- article
- Field-Weighted Citation Impact
- 7.00
Funders
- Science and Technology Development Fund