Abstract 2917 Nanostructured Fullerene-Chitosan Hydrogel: A Minimally Invasive Therapeutic for Degenerative Spine Diseases
Current pain management treatments for intervertebral disc degeneration (IVDD) are often short-lived, costly, and do not address the underlying causes of the condition. Patients typically rely on NSAIDs, corticosteroids, or opioids, which can have significant side effects, carry a risk of dependence, and become less effective over time. These treatments fail to prevent further progression of the disease, leaving patients trapped in a cycle of recurring pain and disability. Surgical alternatives, such as spinal fusion or artificial disc replacement, are invasive, costly, and require long recovery times.
Authors
- Kira Kornienko
Institutions
- Rutgers, The State University of New Jersey (US)
- University of New Brunswick (CA)
- Morehouse School of Medicine (US)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jbc.2025.109088
- Primary Topic
- Graphene and Nanomaterials Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00