Abstract 2917 Nanostructured Fullerene-Chitosan Hydrogel: A Minimally Invasive Therapeutic for Degenerative Spine Diseases

Current pain management treatments for intervertebral disc degeneration (IVDD) are often short-lived, costly, and do not address the underlying causes of the condition. Patients typically rely on NSAIDs, corticosteroids, or opioids, which can have significant side effects, carry a risk of dependence, and become less effective over time. These treatments fail to prevent further progression of the disease, leaving patients trapped in a cycle of recurring pain and disability. Surgical alternatives, such as spinal fusion or artificial disc replacement, are invasive, costly, and require long recovery times.

Authors

Institutions

Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.109088
Primary Topic
Graphene and Nanomaterials Applications
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Abstract 2917 Nanostructured Fullerene-Chitosan Hydrogel: A Minimally Invasive Therapeutic for Degenerative Spine Diseases

Kira Kornienko
Journal of Biological Chemistry
Graphene and Nanomaterials Applications
article

Abstract 2917 Nanostructured Fullerene-Chitosan Hydrogel: A Minimally Invasive Therapeutic for Degenerative Spine Diseases

Kira Kornienko
article en

Abstract

Current pain management treatments for intervertebral disc degeneration (IVDD) are often short-lived, costly, and do not address the underlying causes of the condition. Patients typically rely on NSAIDs, corticosteroids, or opioids, which can have significant side effects, carry a risk of dependence, and become less effective over time. These treatments fail to prevent further progression of the disease, leaving patients trapped in a cycle of recurring pain and disability. Surgical alternatives, such as spinal fusion or artificial disc replacement, are invasive, costly, and require long recovery times.

Journal of Biological ChemistryVol. 301(5)
Rutgers, The State University of New Jersey (US), University of New Brunswick (CA), Morehouse School of Medicine (US)
Zero hunger
Openalex Percentile: Top 87%
Graphene and Nanomaterials Applications
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.