Mobilization of the environmental toxicant chlorpyrifos during weight loss and its impact on liver and adipose tissue metabolism in mice
Weight loss mobilizes CPF and its metabolites from fat stores, leading to tissue accumulation and damage. Even low-dose exposure contributes to hepatic and metabolic disruption in mice, highlighting a potential risk of toxicant mobilization during fat reduction.. https://doi.org/10.1289/EHP16079.
Authors
- Xiaohu Hu (ORCID: https://orcid.org/0000-0002-4720-7848)
- Long Cheng (ORCID: https://orcid.org/0000-0001-9353-8966)
- Yanrong Feng
- Zongyou Jiang
- Zhongzuo Huang (ORCID: https://orcid.org/0000-0002-3521-1209)
- Ying Qian (ORCID: https://orcid.org/0000-0002-8050-2283)
- Yue Lv (ORCID: https://orcid.org/0000-0002-0476-867X)
- Gaojian Tang
- Xin Yu (ORCID: https://orcid.org/0000-0002-8718-0715)
- Bo Wang (ORCID: https://orcid.org/0000-0003-0604-1607)
- B. Li (ORCID: https://orcid.org/0000-0002-1974-2229)
- Yan Zhang (ORCID: https://orcid.org/0000-0002-8038-9663)
- Yicheng Luo
- Yang Xiang
- Xiaoxiao Yu (ORCID: https://orcid.org/0000-0003-4103-2845)
- Xiaoying Sun
Institutions
- Chinese Academy of Sciences (CN)
- Shanghai Institute of Nutrition and Health (CN)
- University of Chinese Academy of Sciences (CN)
- State Key Laboratory of Animal Nutrition
- China Agricultural University (CN)
- Freie Universität Berlin (DE)
Publication Details
- Journal
- Environmental Health Perspectives
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1289/ehp16079
- Primary Topic
- Pesticide Exposure and Toxicity
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Chinese Universities Scientific Fund