Abstract 2638 Characterization of Phosducin-like Protein 3 in Drosophila melanogaster Gametogenesis

Gametogenesis is a critical biological process to all life on earth. Identifying and characterizing the proteins essential to gametogenesis presents an opportunity for exploring the mechanisms controlling cellular development. One such protein, Phosducin-like protein 3 (PhLP3) has been identified by our lab as critical to maintaining fertility in both male and female D. melanogaster. PhLP3 may function as part of a co-chaperone in the folding of actin and tubulin in the chaperone containing tailless (CCT) complex.

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Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.108861
Primary Topic
Neurobiology and Insect Physiology Research
Type
article
Field-Weighted Citation Impact
0.00

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Abstract 2638 Characterization of Phosducin-like Protein 3 in Drosophila melanogaster Gametogenesis

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Abstract 2638 Characterization of Phosducin-like Protein 3 in Drosophila melanogaster Gametogenesis

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article en

Abstract

Gametogenesis is a critical biological process to all life on earth. Identifying and characterizing the proteins essential to gametogenesis presents an opportunity for exploring the mechanisms controlling cellular development. One such protein, Phosducin-like protein 3 (PhLP3) has been identified by our lab as critical to maintaining fertility in both male and female D. melanogaster. PhLP3 may function as part of a co-chaperone in the folding of actin and tubulin in the chaperone containing tailless (CCT) complex.

Journal of Biological ChemistryVol. 301(5)
Loyola University Chicago (US)
National Science Foundation
Zero hunger
Openalex Percentile: Top 85%
Neurobiology and Insect Physiology Research
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