Abstract 1105 Adipose stem cells from the human omentum secrete exosomes to promote healing by regulating apoptosis and immune response pathways in vivo

The omental adipose depot, a visceral adipose tissue, surrounds lower abdomen organs such as the colon, small intestine, spleen, bladder, and reproductive organs. The omentum is known to respond to internal injuries and infections by walling off injuries and by absorbing bacteria and other foreign material. Further, it has been documented that the omentum moves about peritoneal cavity to aid in its response to injuries and infections. Due to its functions in combating internal injuries, we aimed to understand the molecular mechanisms that were associated with the exosomes released from the omental adipose stem cells (om-hASCexo).

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.108790
Primary Topic
Cardiovascular Disease and Adiposity
Type
article
Field-Weighted Citation Impact
0.00

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Abstract 1105 Adipose stem cells from the human omentum secrete exosomes to promote healing by regulating apoptosis and immune response pathways in vivo

Niketa Patel, Brenna Osborne, Bangmei Wang, Paul Albear et al.
Journal of Biological Chemistry
Cardiovascular Disease and Adiposity
article

Abstract 1105 Adipose stem cells from the human omentum secrete exosomes to promote healing by regulating apoptosis and immune response pathways in vivo

Niketa Patel, Brenna Osborne, Bangmei Wang, Paul Albear, Meredith Krause‐Hauch, Rekha Patel
article en

Abstract

The omental adipose depot, a visceral adipose tissue, surrounds lower abdomen organs such as the colon, small intestine, spleen, bladder, and reproductive organs. The omentum is known to respond to internal injuries and infections by walling off injuries and by absorbing bacteria and other foreign material. Further, it has been documented that the omentum moves about peritoneal cavity to aid in its response to injuries and infections. Due to its functions in combating internal injuries, we aimed to understand the molecular mechanisms that were associated with the exosomes released from the omental adipose stem cells (om-hASCexo).

Journal of Biological ChemistryVol. 301(5)
National Institutes of Health, National Eye Institute
Zero hunger
Openalex Percentile: Top 76%
Cardiovascular Disease and Adiposity
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Abstract 1105 Adipose stem cells from the human omentum secrete exosomes to promote healing by regulating apoptosis and immune response pathways in vivo — Niketa Patel, Brenna Osborne, et al. · Journal of Biological Chemistry (2025) | TGRS Research Map | TGRS