Abstract 2441 Observing the effect of palmitoylation on apoptosis levels in ovarian cancer

In women, ovarian cancer is known to be one of the most lethal gynecological cancers. Poor prognosis and high resistance to treatments such as chemotherapy leads to a high lethality. Current research aims to decrease the resistance of ovarian cancer cells against common treatments to improve the clinical outcomes of patients. Studies have shown that the addition of lipids on certain proteins is an important post-translational modification, adding an additional level of regulation. Palmitoylation, a reversible process in which the 16-carbon palmitate is added to a cysteine residue, has been shown to impact apoptosis and cell viability in cancer cells.