Abstract 1696 EHD1 AS A NOVEL REGULATOR OF MICROTUBULE DYNAMICS

Microtubules are dynamic, polar, polymeric filaments assembled from tubulins that are indispensable for intra-cellular trafficking, cell division, motility and sensory functions. Microtubules also comprise the primary cilium, a solitary, immotile structure that serves as a sensory organelle in almost every cell type. A series of microtubule associated proteins (MAPs) including kinesins, dyneins, End Binding Proteins and others regulate microtubule stability, assembly and disassembly, cargo transport, and cell division.