Abstract 2548 Combination of Phytochemicals Inhibits Colorectal Cancer in an In Vivo Model

Colorectal cancer (CRC) rates are decreasing in the elderly but increasing in people under the age of 50. Genetic predisposition contributes 5-10% to CRC development, but the remaining 90-95% is due to diet and lifestyle. Phytochemicals are natural bioactive components present in foods such as vegetables, fruits, whole grains, spices, and medicinal plants. Epidemiological studies show that populations consuming larger amounts of spices and vegetables have a low incidence of CRC, suggesting that phytochemicals offer preventative approaches to cancer.

Authors

Institutions

Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.108738
Primary Topic
Nutrition, Genetics, and Disease
Type
article
Field-Weighted Citation Impact
0.00

Funders

Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Abstract 2548 Combination of Phytochemicals Inhibits Colorectal Cancer in an In Vivo Model

Uthayashanker Ezekiel, Alhan Sayyed, Rita M. Heuertz
Journal of Biological Chemistry
Nutrition, Genetics, and Disease
article

Abstract 2548 Combination of Phytochemicals Inhibits Colorectal Cancer in an In Vivo Model

Uthayashanker Ezekiel, Alhan Sayyed, Rita M. Heuertz
article en

Abstract

Colorectal cancer (CRC) rates are decreasing in the elderly but increasing in people under the age of 50. Genetic predisposition contributes 5-10% to CRC development, but the remaining 90-95% is due to diet and lifestyle. Phytochemicals are natural bioactive components present in foods such as vegetables, fruits, whole grains, spices, and medicinal plants. Epidemiological studies show that populations consuming larger amounts of spices and vegetables have a low incidence of CRC, suggesting that phytochemicals offer preventative approaches to cancer.

Journal of Biological ChemistryVol. 301(5)
California State University, Northridge (US)
U.S. Department of Defense
Zero hunger
Openalex Percentile: Top 84%
Nutrition, Genetics, and Disease
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.