Abstract 1644 Antimicrobial Peptides' Effects on Select ESKAPE Pathogens

Antimicrobial resistance (AMR) continues to be a global health concern projected to rise. Bacterial strains have acquired resistance to commonly prescribed small molecule antibiotics due to misuse, overprescription, and their innate ability to evolve quickly to survive. In this research, the antimicrobial peptide, Melittin and a peptide sequence from neuronal Nitric Oxide Synthase (nNOS), were investigated for their potential to combat AMR in select ESKAPE pathogens [(E. faecalis (ATCC 29212), Staphylococcus aureus (ATCC 29213), Klebsiella pneumoniae (ATCC 13883), Acinebacter baumannii (ATCC 19606)], and E.