Abstract 1394 Cannabidiol enhances lipid droplet deposition along with the expression of FABP4 and AGPAT in 3T3-L1 preadipocytes
Cannabidiol (CBD), a non-psychoactive compound from the Cannabis sativa plant, has emerged as a potential therapeutic agent due to its regulatory effects on various metabolic processes. This study explored the influence of CBD on adipocyte differentiation by examining its effects on two key differentiation markers: Fatty Acid Binding Protein 4 (FABP4) and 1-Acylglycerol-3-Phosphate Acyltransferase (AGPAT). FABP4 is integral to fatty acid transport and lipid storage within adipocytes, while AGPAT plays a pivotal role in phospholipid and triglyceride biosynthesis, essential for lipid accumulation.
Authors
- Nickawn Namdar
Institutions
- Denison University (US)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jbc.2025.108799
- Primary Topic
- Lipid metabolism and biosynthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.00