Abstract 1006 β-carotene reduces ethanol damage in β-cells and increases insulin sensitivity even during ethanol consumption
Alcohol is believed to harm acinar cells, pancreatic ductal epithelium, and pancreatic stellate cells. After giving ethanol and/or β-carotene to C57BL/6 (Mus musculus) mice, our goal was to look at the biochemistry and histology of their blood, as well as the morpho-quantitative features and insulin expression in the pancreas. There were six groups of C57BL/6 mice (n = 36) who were randomly included as follows: 1. Group C (control), 2. Group LA (low-dose alcohol), 3. Group MA (moderate-dose alcohol), 4.
Authors
- Karina Godoy (ORCID: https://orcid.org/0000-0003-4208-4540)
- Cristian Sandoval (ORCID: https://orcid.org/0000-0003-3184-6482)
- Jorge G. Farías (ORCID: https://orcid.org/0000-0001-7660-9603)
- Florencia Carmine
- José Carlos Caamaño (ORCID: https://orcid.org/0000-0002-9572-9982)
- Bélgica Vásquez (ORCID: https://orcid.org/0000-0002-4106-3548)
- Katherine Birditt
- Mauricio Zamorano (ORCID: https://orcid.org/0000-0002-4559-4653)
Publication Details
- Journal
- Journal of Biological Chemistry
- Published
- 2025-05-01
- DOI
- https://doi.org/10.1016/j.jbc.2025.109008
- Primary Topic
- Adipose Tissue and Metabolism
- Type
- article
- Field-Weighted Citation Impact
- 0.00