Abstract 1823 Automating Aptamer Information Extraction Using Fine-Tuned GPT-4o Mini for the UTexas Aptamer Database

Aptamers are oligonucleotide sequences with specific target-binding affinities, offering significant potential in diagnostics, therapeutics, and drug delivery. The UTexas Aptamer Database provides a centralized repository for aptamer-related data, critical for advancing research in these fields. However, its current reliance on manual data extraction from scientific literature limits scalability and introduces inefficiencies. To address this, we aim to develop a fine-tuned Large Language Model (LLM) to automate literature parsing, accelerating database curation and enhancing research accessibility.

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Publication Details

Journal
Journal of Biological Chemistry
Published
2025-05-01
DOI
https://doi.org/10.1016/j.jbc.2025.108979
Primary Topic
Graph Theory and Algorithms
Type
article
Field-Weighted Citation Impact
0.00
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Abstract 1823 Automating Aptamer Information Extraction Using Fine-Tuned GPT-4o Mini for the UTexas Aptamer Database

Dhruv Kumar, Gwendolyn M. Stovall, Angela Wu, Amrut Pennaka
Journal of Biological Chemistry
Graph Theory and Algorithms
article

Abstract 1823 Automating Aptamer Information Extraction Using Fine-Tuned GPT-4o Mini for the UTexas Aptamer Database

Dhruv Kumar, Gwendolyn M. Stovall, Angela Wu, Amrut Pennaka
article en

Abstract

Aptamers are oligonucleotide sequences with specific target-binding affinities, offering significant potential in diagnostics, therapeutics, and drug delivery. The UTexas Aptamer Database provides a centralized repository for aptamer-related data, critical for advancing research in these fields. However, its current reliance on manual data extraction from scientific literature limits scalability and introduces inefficiencies. To address this, we aim to develop a fine-tuned Large Language Model (LLM) to automate literature parsing, accelerating database curation and enhancing research accessibility.

Journal of Biological ChemistryVol. 301(5)
The University of Texas at Austin (US)
Openalex Percentile: Top 88%
Graph Theory and Algorithms
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