Choroidal Hyperreflective Foci Represent a Common Finding Across Different Types of Macular Atrophy

HRFs represent a common OCT finding in various disorders associated with macular atrophy. Their quantity correlates with atrophy size rather than disease type, suggesting they are likely normal choroidal components rendered visible by RPE loss. Future studies are warranted to elucidate their origin and potential implications for disease progression.

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Publication Details

Journal
Investigative Ophthalmology & Visual Science
Published
2025-06-13
DOI
https://doi.org/10.1167/iovs.66.6.42
Citations
2
Primary Topic
Retinal Diseases and Treatments
Type
article
Field-Weighted Citation Impact
3.41
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OCT
article

Choroidal Hyperreflective Foci Represent a Common Finding Across Different Types of Macular Atrophy

Alessandro Arrigo, Enrico Borrelli, Maurízio Battaglia Parodi, Francesco Bandello et al.
2 citations
Investigative Ophthalmology & Visual Science
Retinal Diseases and Treatments
3.41
article

Choroidal Hyperreflective Foci Represent a Common Finding Across Different Types of Macular Atrophy

Alessandro Arrigo, Enrico Borrelli, Maurízio Battaglia Parodi, Francesco Bandello, Paola Marolo, Michele Reibaldi, Elisabetta Miserocchi, Lorena Ulla, Claudio Foti, Maria Vittoria Cicinelli, Mario Peronetti
article en
2 citations

Abstract

HRFs represent a common OCT finding in various disorders associated with macular atrophy. Their quantity correlates with atrophy size rather than disease type, suggesting they are likely normal choroidal components rendered visible by RPE loss. Future studies are warranted to elucidate their origin and potential implications for disease progression.

Investigative Ophthalmology & Visual ScienceVol. 66(6)
Vita-Salute San Raffaele University (IT), Biruni University (TR), Piedmont Reference Center for Epidemiology and Cancer Prevention (IT), Istituti di Ricovero e Cura a Carattere Scientifico (IT), Istituto di Ricovero e Cura a Carattere Scientifico San Raffaele (IT), University of Turin (IT)
Openalex Percentile: Top 8%
Retinal Diseases and Treatments
3.41
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