The impact of anti-M antibodies on patient blood typing and transfusion safety: a retrospective study

In specimens with irregular anti-M antibodies, serum absorption can be used to eliminate the interference caused by the irregular antibodies and obtain the correct experimental results. Moreover, the addition of type O red blood cells in the experiment can improve the detection rate of partial antibodies. For specific patients, such as individuals undergoing surgery, regardless of whether the antibody reacts at 37 °C, we recommend choosing M antigen-negative donors for blood transfusion to ensure the safety of blood transfusion for patients in clinical settings.