Synthesis and Antiproliferative Activity against Melanoma Cells of New Heterocyclic Hybrids Based on Pyridine and Pyrimidine Scaffolds

This research reinforced the significance of heterocyclic rings as valuable pharmacophores. Additionally, it highlighted the antiproliferative and antimitotic potential of modified pyridine derivatives.

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Publication Details

Journal
Current Medicinal Chemistry
Published
2025-06-13
DOI
https://doi.org/10.2174/0109298673370617250330151330
Primary Topic
Synthesis and biological activity
Type
article
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article

Synthesis and Antiproliferative Activity against Melanoma Cells of New Heterocyclic Hybrids Based on Pyridine and Pyrimidine Scaffolds

Zofia M. Myk, Tomasz J. Idzik, Patrycja Kłos, Radosław Birger et al.
Current Medicinal Chemistry
Synthesis and biological activity
article

Synthesis and Antiproliferative Activity against Melanoma Cells of New Heterocyclic Hybrids Based on Pyridine and Pyrimidine Scaffolds

Zofia M. Myk, Tomasz J. Idzik, Patrycja Kłos, Radosław Birger, Jacek G. Sośnicki, Łukasz Struk, Dariusz Chlubek, Magdalena M. Lubowicz, Marek Droździk, Magdalena Perużyńska
article en

Abstract

This research reinforced the significance of heterocyclic rings as valuable pharmacophores. Additionally, it highlighted the antiproliferative and antimitotic potential of modified pyridine derivatives.

Current Medicinal ChemistryVol. 33(5)
University of Szczecin (PL), West Pomeranian University of Technology in Szczecin (PL), Pomeranian Medical University (PL)
Openalex Percentile: Top 90%
Synthesis and biological activity
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