Engineered sEVs encapsulated in GelMA facilitated diabetic wound healing by promoting angiogenesis via targeting thrombospondin-1
This study demonstrated the successful fabrication of a novel bioactive wound dressing (G-miR-221<sup>OE</sup>-sEVs), which promotes diabetic wound healing by promoting angiogenesis through the regulation of TSP-1. This approach offers a potential therapeutic option for enhancing the management of diabetic wounds.
Authors
- Guoqing Yang (ORCID: https://orcid.org/0000-0002-3633-2184)
- Cong Yan (ORCID: https://orcid.org/0000-0002-2848-847X)
- Wandi Li (ORCID: https://orcid.org/0000-0002-2447-7714)
- Yucong Li (ORCID: https://orcid.org/0000-0003-4621-5579)
- Sheng Meng (ORCID: https://orcid.org/0000-0001-5206-7205)
- Xiaoye Xie (ORCID: https://orcid.org/0000-0001-8285-0962)
- Qian Wei (ORCID: https://orcid.org/0009-0001-6720-3721)
- Chuanan Shen (ORCID: https://orcid.org/0000-0001-8298-8355)
- Yiqi Chen (ORCID: https://orcid.org/0009-0008-1808-0500)
- Yingqian Zhou
- Lipeng Zhang
Institutions
- Chinese PLA General Hospital (CN)
- Hainan General Hospital (CN)
- Hainan 301 Hospital (CN)
- Northern Jiangsu People's Hospital (CN)
Publication Details
- Journal
- Burns & Trauma
- Published
- 2025-01-01
- DOI
- https://doi.org/10.1093/burnst/tkaf036
- Citations
- 1
- Primary Topic
- Wound Healing and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.03
Funders
- General Hospital of People’s Liberation Army