Plasma Proteomics Reveals Dysregulated Pathways Across the Spectrum <i>LMNA</i> Cardiomyopathy
Proteomic profiling in individuals with likely pathogenic/pathogenic <i>LMNA</i> variants illuminated integral pathways across the spectrum of <i>LMNA</i> DCM. These findings may help advance genotype-driven biomarker discovery and tailored therapeutic development in <i>LMNA</i> DCM.
Authors
- Carolyn Yung Ho (ORCID: https://orcid.org/0000-0002-7334-7924)
- Christine E. Seidman (ORCID: https://orcid.org/0000-0001-6380-1209)
- Jacob L. Barber (ORCID: https://orcid.org/0000-0002-8132-1601)
- Usman A. Tahir (ORCID: https://orcid.org/0000-0002-3657-6082)
- Laurie Farrell (ORCID: https://orcid.org/0000-0002-5717-527X)
- Joshen Patel (ORCID: https://orcid.org/0000-0001-5086-2002)
- Robert E. Gerszten (ORCID: https://orcid.org/0000-0002-6767-7687)
- Neal K. Lakdawala (ORCID: https://orcid.org/0000-0001-6458-5421)
- Gaurav Tiwari (ORCID: https://orcid.org/0009-0000-2540-6005)
- Julia E. Marine
- Catherine G. Ireland
- Daniel Reichart (ORCID: https://orcid.org/0000-0002-8559-5888)
- Anisha Purohit (ORCID: https://orcid.org/0000-0002-8029-8358)
- Darius Roy (ORCID: https://orcid.org/0009-0004-0978-1664)
Institutions
- Brigham and Women's Hospital (US)
- Beth Israel Deaconess Medical Center (US)
- Harvard University (US)
Publication Details
- Journal
- Circulation Genomic and Precision Medicine
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1161/circgen.124.004924
- Primary Topic
- Viral Infections and Immunology Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00