Causal relationships between metabolic syndrome, plasma metabolites, and female reproductive diseases: insights from a two-step mendelian randomization approach
This investigation established that MetS causally elevates the risk of certain female reproductive diseases and identified plasma metabolites that influence these conditions. These findings enhance the understanding of the etiological pathways involved in MetS and reproductive disorders, highlighting plasma metabolites as potential biomarkers or therapeutic targets.
Authors
- Panwei Hu (ORCID: https://orcid.org/0000-0002-2101-0481)
- Li Li (ORCID: https://orcid.org/0000-0002-0563-4120)
- Qinhua Zhang
- Ningyu Sun (ORCID: https://orcid.org/0000-0002-8723-9529)
- Yi Lin (ORCID: https://orcid.org/0000-0002-1556-6416)
- Juanjuan Ma (ORCID: https://orcid.org/0009-0000-0265-7426)
Institutions
- Shanghai University of Traditional Chinese Medicine (CN)
- Shuguang Hospital (CN)
Publication Details
- Journal
- Nutrition & Metabolism
- Published
- 2025-06-13
- DOI
- https://doi.org/10.1186/s12986-025-00955-8
- Citations
- 1
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 1.82
Funders
- Science and Technology Commission of Shanghai Municipality