Serosurveillance Identifies an Endemic Hotspot of Lassa Fever in Faranah, Upper Guinea
The seroprevalence observed in this study was markedly higher than reported elsewhere in West Africa, identifying Faranah as a hotspot for LASV transmission. Despite the high seroprevalence and estimated force of infection, the number of reported acute cases is very low, suggesting that LASV may frequently cause pauci- or asymptomatic infections or be commonly misdiagnosed for other diseases. These findings underscore that LASV is more widespread than assumed in rural Guinea.
Authors
- Helena Müller-Kräuter (ORCID: https://orcid.org/0009-0009-4134-1729)
- Joachim Mariën (ORCID: https://orcid.org/0000-0001-7023-445X)
- Barré Soropogui
- Stephan Günther (ORCID: https://orcid.org/0000-0002-6562-0230)
- Élisabeth Fichet-Calvet (ORCID: https://orcid.org/0000-0002-9421-3538)
- Matthias Borchert (ORCID: https://orcid.org/0009-0009-3053-9852)
- Beate Becker‐Ziaja (ORCID: https://orcid.org/0000-0002-6971-3178)
- Thomas Strecker (ORCID: https://orcid.org/0000-0002-7857-937X)
- Almudena Marí Sáez (ORCID: https://orcid.org/0000-0002-5429-8485)
- Martin Gabriel
- N’Faly Magassouba
Institutions
- University of Antwerp (BE)
- University of Idaho (US)
- Philipps University of Marburg (DE)
- Université de Montpellier (FR)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Institute for Sustainable Development (ET)
- Institute of Virology of the Slovak Academy of Sciences (SK)
- Institut de Recherche pour le Développement (FR)
- Instituut voor Tropische Geneeskunde (BE)
- Bernhard Nocht Institute for Tropical Medicine (DE)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1093/infdis/jiaf308
- Citations
- 12
- Primary Topic
- Viral Infections and Outbreaks Research
- Type
- article
- Field-Weighted Citation Impact
- 16.75
Funders
- Deutsche Forschungsgemeinschaft
- HORIZON EUROPE Framework Programme
- Departement Economie, Wetenschap en Innovatie