Plasma <scp>microRNA</scp> Signature as Predictive Marker of Clinical Response to Therapy During Multiple Sclerosis
This small exploratory study underscores the potential of plasma circulating miRNAs as candidate biomarkers for predicting therapeutic outcomes in MS and it calls for validation in larger studies, which may enhance our understanding of disease pathophysiology and offer a promising tool for personalized treatment strategies.
Authors
- Gianmarco Abbadessa (ORCID: https://orcid.org/0000-0001-8912-3055)
- Federica Garziano (ORCID: https://orcid.org/0000-0003-0386-7147)
- Assunta Castiello
- Simona Bonavita
- Claudio Procaccini (ORCID: https://orcid.org/0000-0002-2184-0442)
- Alessandra Colamatteo (ORCID: https://orcid.org/0000-0002-9693-3985)
- S. Garavelli (ORCID: https://orcid.org/0000-0001-6105-1467)
- Clorinda Fusco (ORCID: https://orcid.org/0009-0008-2158-4304)
- Teresa Micillo (ORCID: https://orcid.org/0000-0001-5233-8626)
- Claudia La Rocca (ORCID: https://orcid.org/0000-0002-2003-887X)
- Francesco Perna (ORCID: https://orcid.org/0000-0002-2177-1184)
- Paola de Candia (ORCID: https://orcid.org/0000-0003-4767-446X)
- Roberta Lanzillo
- Claudia Russo (ORCID: https://orcid.org/0000-0001-5869-4445)
- Antonio Luca Spiezia (ORCID: https://orcid.org/0000-0003-3287-3247)
- Giuseppe Matarese (ORCID: https://orcid.org/0000-0001-9429-0616)
- Maria Mottola (ORCID: https://orcid.org/0000-0003-3817-7920)
- Fortunata Carbone
- Vincenzo Brescia Morra (ORCID: https://orcid.org/0000-0003-0462-9618)
- Giorgia Teresa Maniscalco (ORCID: https://orcid.org/0000-0002-0679-9939)
Institutions
- Istituto Neurologico Mediterraneo (IT)
- Ospedale Antonio Cardarelli (IT)
- Federico II University Hospital (IT)
- Institute for Experimental Endocrinology and Oncology (IT)
- Ospedale Monaldi (IT)
- Fondazione Santa Lucia (IT)
- Istituti di Ricovero e Cura a Carattere Scientifico (IT)
- Imperial College London (GB)
- University of Naples Federico II (IT)
Publication Details
- Journal
- Annals of Clinical and Translational Neurology
- Published
- 2025-06-11
- DOI
- https://doi.org/10.1002/acn3.70093
- Primary Topic
- MicroRNA in disease regulation
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Biogen
- Università degli Studi di Napoli Federico II
- Fondazione Italiana Sclerosi Multipla
- European Commission
- Ministero della Salute
- Ministero dell'Università e della Ricerca