Hyponatremia Presents With Seizure in a Patient With Arnold-Chiari Malformation: A Case Report
Arnold-Chiari malformation (ACM) is a neuroanatomical disorder characterized by the displacement of cerebellar tonsils through the foramen magnum. While traditionally associated with a spectrum of neurological symptoms, hyponatremic seizures remain a rare and underrecognized presentation of ACM. This manuscript explores the potential pathophysiological mechanisms linking ACM to hyponatremia and presents a clinical case illustrating this unusual association. Although seizures are a well-documented manifestation of various neurological conditions, their occurrence secondary to hyponatremia in ACM patients has not been extensively reported in the literature. By examining this rare complication, we aim to enhance clinical awareness and deepen the understanding of the underlying mechanisms that may contribute to this phenomenon.
Authors
- Mohamed Zuhail K Peediyakkal
- Bara M Al-Qudah (ORCID: https://orcid.org/0000-0001-6697-5853)
- Sunil Hassan Koya
- Abdulqadir J. J. Nashwan (ORCID: https://orcid.org/0000-0003-4845-4119)
- Nevin Kannappilly (ORCID: https://orcid.org/0000-0001-7055-8593)
- Humam Rajha
- Nabil Sherif Mahmood
- Ashib Thurakkal
- Saifil Sidhique
Institutions
- Hamad Medical Corporation (QA)
- Qatar University (QA)
Publication Details
- Journal
- Cureus
- Published
- 2025-06-11
- DOI
- https://doi.org/10.7759/cureus.85819
- Primary Topic
- Electrolyte and hormonal disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00