Genetic prediction of blood metabolites and causal relationships with pain associated with temporomandibular disorders: a Mendelian randomization study

This study establishes a causal link between increased levels of these three metabolites and TMD-related pain. Our findings provide new insights into the pathogenesis of TMD and potential therapeutic targets.

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Publication Details

Journal
Journal of Oral & Facial Pain and Headache
Published
2025-01-01
DOI
https://doi.org/10.22514/jofph.2025.034
Primary Topic
Osteoarthritis Treatment and Mechanisms
Type
article
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article

Genetic prediction of blood metabolites and causal relationships with pain associated with temporomandibular disorders: a Mendelian randomization study

Khanh Le, Xue'e Zhang, Weihong Xi
Journal of Oral & Facial Pain and Headache
Osteoarthritis Treatment and Mechanisms
article

Genetic prediction of blood metabolites and causal relationships with pain associated with temporomandibular disorders: a Mendelian randomization study

Khanh Le, Xue'e Zhang, Weihong Xi
article en

Abstract

This study establishes a causal link between increased levels of these three metabolites and TMD-related pain. Our findings provide new insights into the pathogenesis of TMD and potential therapeutic targets.

Journal of Oral & Facial Pain and HeadacheVol. 39(2)
Nanchang University (CN), First Affiliated Hospital of Jiangxi Medical College (CN), Jiangxi Provincial People's Hospital (CN), Jiangxi Chest Hospital (CN), Jiangxi Provincial Institute of Water Sciences (CN)
Openalex Percentile: Top 79%
Osteoarthritis Treatment and Mechanisms
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